Cefprozil: Side effects, precaution, Indication

Sandoz Limited | Cefprozil (Medication)

Cefprozil: Indications

Cefprozil is used to treat a wide variety of bacterial infections. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or overuse of any antibiotic can lead to its decreased effectiveness.

Cefprozil is a semi-synthetic (partially man-made), oral antibiotic of the cephalosporin family. The cephalosporin family includes cephalexin (Keflex), cefaclor (Ceclor), cefuroxime (Zinacef), cefpodoxime (Vantin), cefixime (Suprax), and many other injectable antibiotics. Like other cephalosporins, cefprozil stops bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall.

Cefprozil is active against a very wide spectrum of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes (the cause of strep throat), Hemophilus influenzae (the cause of otitis media, middle ear infection), Moraxella catarrhalis, E. coli, Klebsiella, Proteus mirabilis, Salmonella, Shigella, Clostridium perfringens and difficile, and Neisseria gonorrhoeae. Cefprozil is effective against susceptible bacteria causing infections of the middle ear, tonsils, throat, larynx (laryngitis), bronchi (bronchitis), skin and soft tissues as well as pneumonia….

Cefprozil: Side Effects

The most common side effects are diarrhea or loose stools, nausea, abdominal pain, vomiting, rash and headache.

Rare side effects include abnormal liver tests and allergic reactions. Like most antibiotics cefprozil may cause a condition called pseudomembranous colitis, a potentially serious bacterial infection of the colon. Persons with phenylketonuria should be advised that the suspension contains phenylalanine. Nausea, vomiting, diarrhea, stomach pain, or dizziness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual tiredness/weakness. Tell your doctor immediately if any of these rare but very serious side effects occur: yellowing of the eyes/skin, severe stomach/abdominal pain, persistent nausea/vomiting, dark urine, change in the amount of urine, signs of new infection (e.g., fever, persistent sore throat), easy bruising/bleeding, mental/mood changes (such as confusion).

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool. Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection)….

Cefprozil: Precaution

Before taking cefprozil, tell your doctor or pharmacist if you are allergic to it; or to penicillins or other cephalosporin antibiotics (e.g., cephalexin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, intestinal disease (colitis).
Exenatide (Byetta) may delay or reduce the absorption of cephalosporins. Cephalosporins should be administered one hour before exenatide.

Cefprozil may cause false test results with some tests for sugar in the urine.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor advice.

Probenecid (Benemid) may increase the blood concentration of cefprozil by decreasing excretion of cefprozil by the kidney. This interaction is sometimes used to enhance the effect of cephalosporins. Combining cefprozil with aminoglycosides (for example, tobramycin) produces additive bacterial killing effects but also may increase the risk of harmful effects to the kidney.

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