Depakote: Side effects, precaution, Indication

Sanofi-Aventis | Depakote (Medication)

Depakote: Indications

Depakote/divalproex sodium is used to treat various types of seizure disorders. It is sometimes used together with other seizure medications. Depakote/divalproex sodium affects chemicals in the body that may be involved in causing seizures….

Depakote: Side Effects

Common Depakote side effects may include: shakiness; nausea; headaches; drowsiness; vomiting; weakness; dizziness.

Some other common side effects, may include: hair loss; abdominal pain (or stomach pain); diarrhea or constipation; flu symptoms, such as a fever or chills; infections; double vision; insomnia; indigestion or heartburn; blurred vision; nervousness; weight gain; back pain; coordination problems; uncontrollable eye movements; swelling or water retention in the arms, legs, or feet; memory loss (amnesia); ringing in the ears (tinnitus); increased appetite or loss of appetite; a fever; emotional problems; weight loss….

Depakote: Precaution

You should not take Depakote if you are allergic to divalproex sodium, or if you have liver disease or a urea cycle disorder. Tell your doctor if you have any of these other conditions: a bleeding or blood clotting disorder; a history of head injury, brain disorder, or coma; a family history of a urea cycle disorder or infant deaths with unknown cause; or HIV or CMV (cytomegalovirus) infection.

Depakote has also caused rare cases of life-threatening pancreatitis (inflammation of the pancreas). In rare cases, Depakote has caused life-threatening liver failure, especially in children younger than 2 years old. Children of this age may be at even greater risk for liver problems if they use more than one seizure medication, if they have a metabolic disorder, or if they have a brain disease causing mental impairment (such as Creutzfeldt-Jacob disease, Huntington disease, multiple sclerosis, or a brain injury or infection).

You may have thoughts about suicide while taking Depakote. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed.

Depakote can cause birth defects. During pregnancy and breastfeeding is not recommended to use this medicine without your doctor’s advice….

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