Dilatrate – SR: Side effects, precaution, Indication

Schwarz Pharma | Dilatrate – SR (Medication)

Dilatrate – SR: Indications

Dilatrate – SR/isosorbide dinitrate is indicated for the prevention of angina pectoris due to coronary artery disease. The onset of action of controlled-release oral isosorbide dinitrate is not sufficiently rapid for this product to be useful in aborting an acute anginal episode.

Dilatrate – SR/isosorbide dinitrate can be taken with or without food. The sublingual tablets should be dissolved under the tongue and should not be crushed or chewed. Isosorbide dinitrate sometimes is used for treating congestive heart failure….

Dilatrate – SR: Side Effects

Dilatrate – SR/isosorbide dinitrate may cause a drop in blood pressure when rising from a sitting position (orthostatic hypotension), causing dizziness, palpitations, and weakness.

Headaches are the most common side effect and usually are dose-related (increase with higher doses). Flushing may occur because isosorbide dinitrate dilates blood vessels. To reduce the risk of these side effects, patients should rise slowly from a sitting position….

Dilatrate – SR: Precaution

Patients taking Dilatrate – SR/isosorbide dinitrate should not receive sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra). Sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra) increase the blood pressure lowering effects of isosorbide dinitrate and may cause excessive blood pressure reduction.

Severe hypotension, particularly with upright posture, may occur with even small doses of isosorbide dinitrate. This drug should therefore be used with caution in patients who may be volume depleted or who, for whatever reason, are already hypotensive. Hypotension induced by isosorbide dinitrate may be accompanied by paradoxical bradycardia and increased angina pectoris.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor’s advice….

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