Acetylsalicylic acid: Side effects, precaution, Indication

Riker Laboratories | Acetylsalicylic acid (Medication)

Acetylsalicylic acid: Indications

Acetylsalicylic acid (called also aspirin) is used to treat pain; fever; various inflammatory conditions; reduction of risk of death or MI in patients with previous infarction or unstable angina pectoris, or recurrent transient ischemia attacks (TIAs) or stroke in men who have had transient brain ischemia caused by platelet emboli….

Acetylsalicylic acid: Side Effects

Low-dose aspirin are usually well supported. There have been various reported bleeding – hematemesis, melena, occult GI bleeding (possibly with iron deficiency anemia), epistaxis, gingival bleeding, purpura.

The risk of surgical bleeding is increased. Fostering bleeding lasts for 4-8 days after stopping the aspirin. The phenomena of gastric irritation (abdominal pain, heartburn, nausea, vomiting) are rare when treatment is done correctly. Have been reported to activate peptic ulcer.

Allergic reactions are possible, especially manifested by urticaria, edema, asthma or anaphylactic reactions rarely. Have been reported anaphylactoid reactions in patients idiosyncratic. Infectious complications were reported, including Reye syndrome (encephalopathy and liver damage) in children treated with aspirin in analgesic and antipyretic effect….

Acetylsalicylic acid: Precaution

Medicines containing aspirin may be given to children under 12 years not only on clinical viral diseases, because of the possibility of Reye syndrome, a rare but serious. Aspirin is associated with several suspected or probable interactions that affect the action of other drugs. The following examples are the most common of the suspected interactions.

Aspirin may reduce the blood pressure lowering effects of blood pressure medications. This may occur because prostaglandins have a role in the regulation of blood pressure.

When aspirin is used in combination with methotrexate (Rheumatrex, Trexall) or aminoglycoside antibiotics (for example, gentamicin) the blood levels of the methotrexate or aminoglycoside may increase, presumably because their elimination from the body is reduced. This may lead to more methotrexate or aminoglycoside-related side effects.

Individuals taking oral blood thinners or anticoagulants, for example, warfarin, should avoid aspirin because aspirin also thins the blood, and excessive blood thinning may lead to serious bleeding.

During pregnancy and breastfeeding is not recommended to use this medicine without your doctor’s advice….

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