Capreomycin injection: Side effects, precaution, Indication

Harvard Drug Group Pharmaceutical | Capreomycin injection (Medication)

Capreomycin injection: Indications

Capreomycin is indicated in combination with other antituberculosis medications in the treatment of pulmonary tuberculosis caused by Mycobacterium tuberculosis after failure with the primary medications (streptomycin, isoniazid, rifampin, pyrazinamide, and ethambutol) or when these cannot be used because of toxicity or development of resistant tubercle bacilli….

Capreomycin injection: Side Effects

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing….

Capreomycin injection: Precaution

Elderly people may be at a greater risk for side effects while using this drug. During pregnancy and breastfeeding is not recommended to use this medicine without your doctor advice.

The use of capreomycin in patients with renal insufficiency or pre-existing auditory impairment must be undertaken with great caution, and the risk of additional eighth cranial nerve impairment or renal injury should be weighed against the benefits to be derived from treatment.

Capreomycin must be used only in conjunction with adequate doses of other antituberculous drugs. The use of Capreomycin alone allows the rapid development of strains resistant to it.

As capreomycin is potentially ototoxic, audiometry and assessment of vestibular function should be performed before starting treatment and at regular intervals during treatment.

Regular tests of renal function should be made throughout the period of treatment, and reduced dosage should be used in patients known, or suspected, renal impairment….